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Calcium channel-modulator-1
CAS No. 136941-70-3
Calcium channel-modulator-1( —— )
Catalog No. M32746 CAS No. 136941-70-3
Calcium channel-modulator-1, a calcium channel-modulator (IC50: 0.8 μM), specializes in blocking aortic constriction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 332 | In Stock |
|
| 5MG | 258 | In Stock |
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| 10MG | 416 | In Stock |
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| 25MG | 708 | In Stock |
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| 50MG | 918 | In Stock |
|
| 100MG | 1293 | In Stock |
|
| 200MG | 1739 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCalcium channel-modulator-1
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NoteResearch use only, not for human use.
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Brief DescriptionCalcium channel-modulator-1, a calcium channel-modulator (IC50: 0.8 μM), specializes in blocking aortic constriction.
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DescriptionCalcium channel-modulator-1 is a calcium channel modulator; blocks aortic contraction with an IC50 of 0.8 μM.
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In Vitro——
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In VivoOral administration of Calcium channel-modulator-1 (20 mg/kg) causes a 35-37% decrease in systolic blood pressure in spontaneously hypertensive rats. However, iv administration of Calcium channel-modulator-1 to anesthetized spontaneously hypertensive rats causes a decrease in blood pressure which was more pronounced and long-lasting than that of nifedipine.
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Synonyms——
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number136941-70-3
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Formula Weight579.45
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Molecular FormulaC26H24Cl2N2O7S
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Purity>98% (HPLC)
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Solubility——
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SMILESC(OCCCN1S(=O)(=O)C=2C(C1=O)=CC=CC2)(=O)C=3C(C(C(OC)=O)=C(C)NC3C)C4=C(Cl)C(Cl)=CC=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sunkel CE, et al. Synthesis of 3-[(2,3-dihydro-1,1,3-trioxo-1,2-benzisothiazol-2-yl)alkyl] 1,4-dihydropyridine-3,5-dicarboxylate derivatives as calcium channel modulators. J Med Chem. 1992 Jun 26;35(13):2407-14.?
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