Cart
sales@molnova.com
Praeruptorin A (c)
CAS No. 14017-71-1
Praeruptorin A (c)( ——— )
Catalog No. M38912 CAS No. 14017-71-1
(-)-Praeruptorin A is a nature product that could be isolated from the roots of Peucedanum praeruptorum Dunn. (-)-Praeruptorin A relaxes ileum and tracheal smooth muscles by activating NO/cGMP signaling pathway. (-)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca2+-influx blocker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 258 | Get Quote |
|
| 25MG | Get Quote | Get Quote |
|
| 50MG | Get Quote | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePraeruptorin A (c)
-
NoteResearch use only, not for human use.
-
Brief Description(-)-Praeruptorin A is a nature product that could be isolated from the roots of Peucedanum praeruptorum Dunn. (-)-Praeruptorin A relaxes ileum and tracheal smooth muscles by activating NO/cGMP signaling pathway. (-)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca2+-influx blocker.
-
Description(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis;it also can significantly suppress airway inflammation and airway remodeling induced by ovalbumin challenge, and is a potential candidate for the treatment of asthma.
-
In Vitro———
-
In Vivo———
-
Synonyms———
-
PathwayGPCR/G Protein
-
TargetCalcium Channel
-
RecptorATPase;Calcium Channel;IFN-γ;IL Receptor;NO;P-gp;TGF-β/Smad
-
Research Area———
-
Indication———
Chemical Information
-
CAS Number14017-71-1
-
Formula Weight386.4
-
Molecular FormulaC21H22O7
-
Purity>98% (HPLC)
-
Solubility———
-
SMILES———
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Xu Z, et, al. (+/-)-Praeruptorin A enantiomers exert distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis. Chem Biol Interact. 2010 Jul 30;186(2):239-46.?
molnova catalog
related products
-
Lomerizine hydrochlo...
Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine.
-
Mibefradil dihydroch...
Mibefradil dihydrochloride is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type currents with IC50s of 2.7 μM and 18.6 μM, respectively). Mibefradil dihydrochloride inhibits reversibly the T- and L-type currents with IC50 values of 2.7 and 18.6 μM, respectively.
-
Fenoverine
Fenoverine (Spasmopriv) is a novel smooth muscle motor synchronizer with anti-spasmodic activity that inhibits fast and slow Ca2+ channel currents in a concentration-dependent manner and can be used to study gastrointestinal spasms.
