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Bepridil hydrochloride
CAS No. 68099-86-5
Bepridil hydrochloride( CERM 1978 )
Catalog No. M20140 CAS No. 68099-86-5
Bepridil is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX) sodium channels and cardiac sarcolemmal KATP channels.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 10MG | 38 | In Stock |
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| 25MG | 77 | In Stock |
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| 50MG | 105 | In Stock |
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| 100MG | 152 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBepridil hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionBepridil is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX) sodium channels and cardiac sarcolemmal KATP channels.
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DescriptionBepridil is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX) sodium channels and cardiac sarcolemmal KATP channels.(In Vitro):Bepridil hydrochloride is a calcium channel blocker, with antianginal activity.(In Vivo):Bepridil hydrochloride (21 mg/kg) reduces heart rate and mean arterial pressure, decreases the mean coronary vascular resistance and increases stroke volume in rats.
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In VitroBepridil hydrochloride is a calcium channel blocker, with antianginal activity.
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In VivoBepridil hydrochloride (21 mg/kg) reduces heart rate and mean arterial pressure, decreases the mean coronary vascular resistance and increases stroke volume in rats.
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SynonymsCERM 1978
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research AreaCardiovascular Disease
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IndicationAngina pectoris; Tachycardia
Chemical Information
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CAS Number68099-86-5
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Formula Weight403
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Molecular FormulaC24H35ClN2O
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Purity>98% (HPLC)
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SolubilityDMSO: 130 mg/mL (322.58 mM)
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SMILESCl.CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Ticolubant
Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migration with an IC50 of 6.6 ± 1.5 nM, and shows topical anti-inflammatory activity in a mouse model of skin inflammation.
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Mibefradil dihydroch...
Mibefradil dihydrochloride is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type currents with IC50s of 2.7 μM and 18.6 μM, respectively). Mibefradil dihydrochloride inhibits reversibly the T- and L-type currents with IC50 values of 2.7 and 18.6 μM, respectively.
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Diltiazem
Diltiazem (CRD 401 free base) is an orally available L-type Ca2+ channel blocker with antihypertensive, antiarrhythmic, and cardioprotective properties that prevent post-reperfusion myocardial injury, angina pectoris, and cardiovascular-related diseases.
