Cart
sales@molnova.com
CIM0216
CAS No. 1031496-06-6
CIM0216( N-(5-methyl-1,2-oxazol-3-yl)-2-phenyl-2-(1,2,3,4-tetrahydroquinolin-1-yl)acetamide )
Catalog No. M23235 CAS No. 1031496-06-6
CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 49 | In Stock |
|
| 5MG | 76 | In Stock |
|
| 10MG | 133 | In Stock |
|
| 25MG | 282 | In Stock |
|
| 50MG | 441 | In Stock |
|
| 100MG | 664 | In Stock |
|
| 500MG | 1377 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCIM0216
-
NoteResearch use only, not for human use.
-
Brief DescriptionCIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.
-
DescriptionCIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.
-
In Vitro——
-
In Vivo——
-
SynonymsN-(5-methyl-1,2-oxazol-3-yl)-2-phenyl-2-(1,2,3,4-tetrahydroquinolin-1-yl)acetamide
-
PathwayMembrane Transporter/Ion Channel
-
TargetTRP/TRPV Channel
-
RecptorTRPM3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1031496-06-6
-
Formula Weight347.41
-
Molecular FormulaC21H21N3O2
-
Purity>98% (HPLC)
-
SolubilityDMSO: 30 mg/mL?(86.35 mM;?Need ultrasonic and warming);Ethanol: 17 mg/mL?(48.93 mM;?Need ultrasonic and warming)
-
SMILESO=C(NC1=NOC(C)=C1)C(C2=CC=CC=C2)N3CCCC4=C3C=CC=C4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Vriens J , Owsianik G , Hofmann T , et al. TRPM3 is a nociceptor channel involved in the detection of noxious heat.[J]. Neuron, 2011, 70(3):482-494.
molnova catalog
related products
-
Pyr10
Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells (IC50: 0.72 μM) (IC50 of 13.08 μM for store-operated Ca2+ entry in BRL-2H3 cells) .
-
ASP7663
ASP7663 is a?TRPA1 Receptor Agonist?and exhibiting an abdominal analgesic effect in vivo.?
-
JYL 1421
JYL 1421 is an antagonist of TRPV1 receptor (IC50 = 8 nM).
