RN-1734
CAS No. 946387-07-1
RN-1734 ( —— )
Catalog No. M20811 CAS No. 946387-07-1
RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM5.9 μM3.2 μM for hTRPV4 ?mTRPV4 and rTRPV4respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 30 | Get Quote |
|
5MG | 46 | Get Quote |
|
10MG | 67 | Get Quote |
|
25MG | 147 | Get Quote |
|
50MG | 249 | Get Quote |
|
100MG | 372 | Get Quote |
|
500MG | 843 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRN-1734
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NoteResearch use only not for human use.
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Brief DescriptionRN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM5.9 μM3.2 μM for hTRPV4 ?mTRPV4 and rTRPV4respectively).
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DescriptionRN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM5.9 μM3.2 μM for hTRPV4 ?mTRPV4 and rTRPV4respectively).
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetTRP/TRPV Channel
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RecptorhTRPV4
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Research Area——
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Indication——
Chemical Information
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CAS Number946387-07-1
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Formula Weight353.31
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Molecular FormulaC14H22Cl2N2O2S
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (141.52 mM)
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SMILESCC(C)NCCN(C(C)C)S(=O)(=O)c1ccc(Cl)cc1Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Meiying Liu Xuan et al. TRPV4 Inhibition Improved Myelination and Reduced Glia Reactivity and Inflammation in a Cuprizone-Induced Mouse Model of Demyelination.[J]. Frontiers in cellular neuroscience 2018.
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