RN-1734

CAS No. 946387-07-1

RN-1734 ( —— )

Catalog No. M20811 CAS No. 946387-07-1

RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM5.9 μM3.2 μM for hTRPV4 ?mTRPV4 and rTRPV4respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 30 Get Quote
5MG 46 Get Quote
10MG 67 Get Quote
25MG 147 Get Quote
50MG 249 Get Quote
100MG 372 Get Quote
500MG 843 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    RN-1734
  • Note
    Research use only not for human use.
  • Brief Description
    RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM5.9 μM3.2 μM for hTRPV4 ?mTRPV4 and rTRPV4respectively).
  • Description
    RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM5.9 μM3.2 μM for hTRPV4 ?mTRPV4 and rTRPV4respectively).
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    hTRPV4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    946387-07-1
  • Formula Weight
    353.31
  • Molecular Formula
    C14H22Cl2N2O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (141.52 mM)
  • SMILES
    CC(C)NCCN(C(C)C)S(=O)(=O)c1ccc(Cl)cc1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Meiying Liu Xuan et al. TRPV4 Inhibition Improved Myelination and Reduced Glia Reactivity and Inflammation in a Cuprizone-Induced Mouse Model of Demyelination.[J]. Frontiers in cellular neuroscience 2018.
molnova catalog
related products
  • Berbamine

    Berbamine and its derivatives are promising agents to suppress liver cancer growth by targeting CAMKII.

  • RQ00203078

    RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist (IC50 values are 5.3 and 8.3 nM for rat and human channels respectively).

  • SKF-96365 hydrochlor...

    SKF-96365, an SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells.