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RN-1734

CAS No. 946387-07-1

RN-1734 ( —— )

Catalog No. M20811 CAS No. 946387-07-1

RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM5.9 μM3.2 μM for hTRPV4 ?mTRPV4 and rTRPV4respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 46 Get Quote
10MG 67 Get Quote
25MG 147 Get Quote
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Biological Information

  • Product Name
    RN-1734
  • Note
    Research use only not for human use.
  • Brief Description
    RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM5.9 μM3.2 μM for hTRPV4 ?mTRPV4 and rTRPV4respectively).
  • Description
    RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM5.9 μM3.2 μM for hTRPV4 ?mTRPV4 and rTRPV4respectively).
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    hTRPV4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    946387-07-1
  • Formula Weight
    353.31
  • Molecular Formula
    C14H22Cl2N2O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (141.52 mM)
  • SMILES
    CC(C)NCCN(C(C)C)S(=O)(=O)c1ccc(Cl)cc1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Meiying Liu Xuan et al. TRPV4 Inhibition Improved Myelination and Reduced Glia Reactivity and Inflammation in a Cuprizone-Induced Mouse Model of Demyelination.[J]. Frontiers in cellular neuroscience 2018.
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