Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - TRP/TRPV Channel - Capsazepine

Capsazepine

CAS No. 138977-28-3

Capsazepine ( —— )

Catalog No. M20641 CAS No. 138977-28-3

Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM).?Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel.?It is therefore considered to be a capsaicin antagonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 43 In Stock
10MG 68 In Stock
25MG 125 In Stock
50MG 210 In Stock
100MG 339 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Capsazepine
  • Note
    Research use only not for human use.
  • Brief Description
    Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM).?Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel.?It is therefore considered to be a capsaicin antagonist.
  • Description
    Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM).?Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel.?It is therefore considered to be a capsaicin antagonist.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    TRPA1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    138977-28-3
  • Formula Weight
    376.9
  • Molecular Formula
    C19H21ClN2O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (132.66 mM)
  • SMILES
    Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1
  • Chemical Name
    N-[2-(4-Chlorophenyl)ethyl]-1345-tetrahydro-78-dihydroxy-2H-2-benzazepine-2-carbothioamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yang MH Jung SH Sethi Get al.Pleiotropic Pharmacological Actions of Capsazepine a Synthetic Analogue of Capsaicin against Various Cancers and Inflammatory Diseases[J].Molecules. 2019 Mar 12;24(5). pii: E995.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • M-084 hydrochloride

    M-084 hydrochloride is a blocker of TRPC4/5 channel, with antidepressant and anxiolytic effects.

  • Probenecid

    The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate.

  • SKF-96365 hydrochlor...

    SKF-96365, an SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells.

Sign In Join Free