Capsazepine
CAS No. 138977-28-3
Capsazepine ( —— )
Catalog No. M20641 CAS No. 138977-28-3
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM).?Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel.?It is therefore considered to be a capsaicin antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 43 | In Stock |
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10MG | 68 | In Stock |
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25MG | 125 | In Stock |
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50MG | 210 | In Stock |
|
100MG | 339 | In Stock |
|
200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameCapsazepine
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NoteResearch use only not for human use.
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Brief DescriptionCapsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM).?Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel.?It is therefore considered to be a capsaicin antagonist.
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DescriptionCapsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM).?Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel.?It is therefore considered to be a capsaicin antagonist.
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetTRP/TRPV Channel
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RecptorTRPA1
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Research Area——
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Indication——
Chemical Information
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CAS Number138977-28-3
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Formula Weight376.9
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Molecular FormulaC19H21ClN2O2S
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (132.66 mM)
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SMILESOc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1
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Chemical NameN-[2-(4-Chlorophenyl)ethyl]-1345-tetrahydro-78-dihydroxy-2H-2-benzazepine-2-carbothioamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yang MH Jung SH Sethi Get al.Pleiotropic Pharmacological Actions of Capsazepine a Synthetic Analogue of Capsaicin against Various Cancers and Inflammatory Diseases[J].Molecules. 2019 Mar 12;24(5). pii: E995.
molnova catalog
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