C7280948

Research use only, not for human use.

C-7280948 is a PRMT1 inhibitor.

C-7280948 is a PRMT1 inhibitor.

C-7280948 is compound 6a in this article, it against hPRMT1 with an IC50 value of 12.75 μM.Especially arginine methyltransferases also target non-histone protein substrates and are therefore often called protein methyltransferases (PRMTs). The subtype PRMT1 has been linked to the activation of estrogen and androgen receptors and therefore may represent a new treatment option for hormone-dependent cancer.

——

C7280948 | C-7280948 | C 7280948

Chromatin/Epigenetic

HMTase

PRMT1

Cancer

——

587850-67-7

276.35

C14H16N2O2S

>98% (HPLC)

DMSO: 10 mM

O=S(C1=CC=C(N)C=C1)(NCCC2=CC=CC=C2)=O

4-amino-N-phenethylbenzenesulfonamide

(-20℃)

With Ice Pack

≥ 2 years