Bifluranol

CAS No. 34633-34-6

Bifluranol( —— )

Catalog No. M33302 CAS No. 34633-34-6

Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic hyperplasia (BPH).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 231 Get Quote
5MG 359 Get Quote
10MG 588 Get Quote
25MG 1132 Get Quote
50MG 1831 Get Quote
100MG 2412 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Bifluranol
  • Note
    Research use only, not for human use.
  • Brief Description
    Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic hyperplasia (BPH).
  • Description
    Bifluranol (BX341) is an anti-androgen.
  • In Vitro
    ——
  • In Vivo
    The absorption, distribution and excretion of Bifluranol have been studied in mouse, rat, ferret and dog; Bifluranol is readily absorbed following oral administration, but blood concentrations of Bifluranol are low due to hepatic uptake and biliary excretion. After intravenous administration of [3H]Bifluranol to rats (200 μg/kg) and ferrets (60 μg/kg) the blood concentrations of 3H decreases rapidly for the first 2 to 3 h, with the decrease being more rapid in females ( 18 min for rat, 30 min for ferret) than males (1.0 h for rat, 1.4 h for ferret). This is followed by a much slower decline (40 h for rat, 20 h for ferret) to concentrations at 96 h of less than 15 ng Bifluranol equivalents mL-1 (rat) or 1 ng Bifluranol equivalents mL-1 (ferret).
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    Androgen Receptor (AR)
  • Recptor
    Androgen Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    34633-34-6
  • Formula Weight
    292.32
  • Molecular Formula
    C17H18F2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (342.09 mM; Ultrasonic )
  • SMILES
    CC[C@H]([C@H](C)c1ccc(O)c(F)c1)c1ccc(O)c(F)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pope DJ, et al. Bifluranol, a novel fluorinated bibenzyl anti-androgen, its chemistry and disposition in different animal species. J Pharm Pharmacol. 1981 May;33(5):297-301.?
molnova catalog
related products
  • LY2452473

    LY2452473 (TT 701;OPK 88004) is an orally bioavailable selective androgen receptor modulator (SARM) being developed for the treatment of disorders related to hypogonadism.

  • Mesterolone

    Mesterolone is an orally applicable androgen and dihydrotestosterone (DHT) derivative.

  • ORM-15341

    The active main metabolite of ODM-201, a potent wt/mutant androgen receptor (AR) inhibitor.