
Bifluranol
CAS No. 34633-34-6
Bifluranol( —— )
Catalog No. M33302 CAS No. 34633-34-6
Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic hyperplasia (BPH).
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 231 | Get Quote |
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5MG | 359 | Get Quote |
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10MG | 588 | Get Quote |
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25MG | 1132 | Get Quote |
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50MG | 1831 | Get Quote |
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100MG | 2412 | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameBifluranol
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NoteResearch use only, not for human use.
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Brief DescriptionBifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic hyperplasia (BPH).
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DescriptionBifluranol (BX341) is an anti-androgen.
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In Vitro——
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In VivoThe absorption, distribution and excretion of Bifluranol have been studied in mouse, rat, ferret and dog; Bifluranol is readily absorbed following oral administration, but blood concentrations of Bifluranol are low due to hepatic uptake and biliary excretion. After intravenous administration of [3H]Bifluranol to rats (200 μg/kg) and ferrets (60 μg/kg) the blood concentrations of 3H decreases rapidly for the first 2 to 3 h, with the decrease being more rapid in females ( 18 min for rat, 30 min for ferret) than males (1.0 h for rat, 1.4 h for ferret). This is followed by a much slower decline (40 h for rat, 20 h for ferret) to concentrations at 96 h of less than 15 ng Bifluranol equivalents mL-1 (rat) or 1 ng Bifluranol equivalents mL-1 (ferret).
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetAndrogen Receptor (AR)
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RecptorAndrogen Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number34633-34-6
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Formula Weight292.32
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Molecular FormulaC17H18F2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (342.09 mM; Ultrasonic )
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SMILESCC[C@H]([C@H](C)c1ccc(O)c(F)c1)c1ccc(O)c(F)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pope DJ, et al. Bifluranol, a novel fluorinated bibenzyl anti-androgen, its chemistry and disposition in different animal species. J Pharm Pharmacol. 1981 May;33(5):297-301.?
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