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LGD-3303

CAS No. 917891-35-1

LGD-3303( LGD3303 )

Catalog No. M16590 CAS No. 917891-35-1

LGD-3303 is an orally available, brain-penetrant nonsteroidal selective androgen receptor modulator (SARM) that that shows little or no cross-reactivity with related nuclear receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    LGD-3303
  • Note
    Research use only, not for human use.
  • Brief Description
    LGD-3303 is an orally available, brain-penetrant nonsteroidal selective androgen receptor modulator (SARM) that that shows little or no cross-reactivity with related nuclear receptors.
  • Description
    LGD-3303 is an orally available, brain-penetrant nonsteroidal selective androgen receptor modulator (SARM) that that shows little or no cross-reactivity with related nuclear receptors; has potent activity on levator ani muscle but is a partial agonist on the preputial gland and ventral prostate in a castrated rat model of androgen deficiency; enhances male-directed sexual preference, proceptive behavior, and lordosis behavior in sexually experienced, but not sexually naive, female rats.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    LGD3303
  • Pathway
    Endocrinology/Hormones
  • Target
    Androgen Receptor (AR)
  • Recptor
    AndrogenReceptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    917891-35-1
  • Formula Weight
    342.743
  • Molecular Formula
    C16H14ClF3N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: Soluble （ < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    O=C1NC2=C(C3=C(N(CC(F)(F)F)C(CC)=C3C)C=C2)C(Cl)=C1
  • Chemical Name
    9-Chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H-pyrrolo(3,2-F)quinolin-7(6H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Vajda EG, et al. J Pharmacol Exp Ther. 2009 Feb;328(2):663-70. 2. Vajda EG, et al. J Bone Miner Res. 2009 Feb;24(2):231-40. 3. Kudwa AE, et al. Endocrinology. 2010 Jun;151(6):2659-68.
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