BML-210

CAS No. 537034-17-6

BML-210 ( BML210;BML 210 )

Catalog No. M14907 CAS No. 537034-17-6

A novel histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 31 In Stock
5MG 48 In Stock
10MG 69 In Stock
25MG 115 In Stock
50MG 186 In Stock
100MG 332 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BML-210
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM.
  • Description
    A novel histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM; inhibits the growth of all cell lines and promotes apoptosis in the human leukemia cell lines (NB4, HL-60, THP-1, and K562); induces growth inhibition and apoptosis and downregulates HDAC1-5 and DAPC complex expression levels in cervical cancer cells.
  • Synonyms
    BML210;BML 210
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    537034-17-6
  • Formula Weight
    339.43
  • Molecular Formula
    C20H25N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 30 mg/mL
  • SMILES
    O=C(NC1=CC=CC=C1N)CCCCCCC(NC2=CC=CC=C2)=O
  • Chemical Name
    Octanediamide, N1-(2-aminophenyl)-N8-phenyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Savickiene J, et al. Eur J Pharmacol. 2006 Nov 7;549(1-3):9-18.
2. Wong JC, et al. J Am Chem Soc. 2003 May 14;125(19):5586-7.
3. Borutinskaite VV, et al. Mol Biol Rep. 2012 Dec;39(12):10179-86.
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