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SIS17
CAS No. 2374313-54-7
SIS17 ( —— )
Catalog No. M20333 CAS No. 2374313-54-7
SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17 is active in cells and inhibited the demyristoylation of a known HDAC11 substrate serine hydroxymethyl transferase 2 without inhibiting other HDACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 53 | In Stock |
|
| 10MG | 88 | In Stock |
|
| 25MG | 170 | In Stock |
|
| 50MG | 290 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSIS17
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NoteResearch use only not for human use.
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Brief DescriptionSIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17 is active in cells and inhibited the demyristoylation of a known HDAC11 substrate serine hydroxymethyl transferase 2 without inhibiting other HDACs.
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DescriptionSIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17 is active in cells and inhibited the demyristoylation of a known HDAC11 substrate serine hydroxymethyl transferase 2 without inhibiting other HDACs.
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC11
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Research Area——
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Indication——
Chemical Information
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CAS Number2374313-54-7
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Formula Weight366.6
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Molecular FormulaC21H38N2OS?
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL?(340.97 mM)
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SMILESCCCCCCCCCCCCCCCCNNC(=O)c1cccs1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Son S I Cao J Zhu C L et al. Activity-Guided Design of HDAC11-Specific Inhibitors[J]. ACS Chemical Biology 2019 14(7):1393-1397.
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