Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - HDAC - SIS17

SIS17

CAS No. 2374313-54-7

SIS17 ( —— )

Catalog No. M20333 CAS No. 2374313-54-7

SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17 is active in cells and inhibited the demyristoylation of a known HDAC11 substrate serine hydroxymethyl transferase 2 without inhibiting other HDACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 53 In Stock
10MG 88 In Stock
25MG 170 In Stock
50MG 290 In Stock
100MG 462 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    SIS17
  • Note
    Research use only not for human use.
  • Brief Description
    SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17 is active in cells and inhibited the demyristoylation of a known HDAC11 substrate serine hydroxymethyl transferase 2 without inhibiting other HDACs.
  • Description
    SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17 is active in cells and inhibited the demyristoylation of a known HDAC11 substrate serine hydroxymethyl transferase 2 without inhibiting other HDACs.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC11
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2374313-54-7
  • Formula Weight
    366.6
  • Molecular Formula
    C21H38N2OS?
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL?(340.97 mM)
  • SMILES
    CCCCCCCCCCCCCCCCNNC(=O)c1cccs1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Son S I Cao J Zhu C L et al. Activity-Guided Design of HDAC11-Specific Inhibitors[J]. ACS Chemical Biology 2019 14(7):1393-1397.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Alteminostat

    Alteminostat is a novel histone deacetylase (HDAC) inhibitor.

  • BML-210

    A novel histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM.

  • BRD2492

    BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively).

Sign In Join Free