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Autogramin-2
CAS No. 2375541-45-8
Autogramin-2( tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate )
Catalog No. M24090 CAS No. 2375541-45-8
Autogramin-2 potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 43 | In Stock |
|
| 5MG | 72 | In Stock |
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| 10MG | 110 | In Stock |
|
| 25MG | 205 | In Stock |
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| 50MG | 335 | In Stock |
|
| 100MG | 507 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAutogramin-2
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NoteResearch use only, not for human use.
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Brief DescriptionAutogramin-2 potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)
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DescriptionAutogramin-2 potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)
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In Vitro——
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In Vivo——
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Synonymstert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
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PathwayAutophagy
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TargetAutophagy
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Recptorautophagy
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Research Area——
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Indication——
Chemical Information
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CAS Number2375541-45-8
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Formula Weight417.52
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Molecular FormulaC21H27N3O4S
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Purity>98% (HPLC)
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SolubilityDMSO:83.33 mg/mL?(199.58 mM;?Need ultrasonic)
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SMILESO=C(N1CCC2=C(SC(NC(C3=CC=C(OC(C)C)C=C3)=O)=N2)C1)OC(C)(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720.
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