Autogramin-2

CAS No. 2375541-45-8

Autogramin-2( tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate )

Catalog No. M24090 CAS No. 2375541-45-8

Autogramin-2 potently inhibits?autophagy?induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 In Stock
5MG 72 In Stock
10MG 110 In Stock
25MG 205 In Stock
50MG 335 In Stock
100MG 507 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Autogramin-2
  • Note
    Research use only, not for human use.
  • Brief Description
    Autogramin-2 potently inhibits?autophagy?induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)
  • Description
    Autogramin-2 potently inhibits?autophagy?induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    autophagy
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2375541-45-8
  • Formula Weight
    417.52
  • Molecular Formula
    C21H27N3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:83.33 mg/mL?(199.58 mM;?Need ultrasonic)
  • SMILES
    O=C(N1CCC2=C(SC(NC(C3=CC=C(OC(C)C)C=C3)=O)=N2)C1)OC(C)(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720.
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