Cart
sales@molnova.com
Dilmapimod
CAS No. 444606-18-2
Dilmapimod( SB-681323 | GW 681323 )
Catalog No. M24403 CAS No. 444606-18-2
Dilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
|
| 5MG | 37 | In Stock |
|
| 10MG | 61 | In Stock |
|
| 25MG | 116 | In Stock |
|
| 50MG | 184 | In Stock |
|
| 100MG | 343 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDilmapimod
-
NoteResearch use only, not for human use.
-
Brief DescriptionDilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
-
DescriptionDilmapimod is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.
-
In VitroDilmapimod (SB-681323) potently inhibits p38 MAPK signaling, measured by inhibition of sorbitol-induced pHSP27 expression.
-
In Vivo——
-
SynonymsSB-681323 | GW 681323
-
PathwayAutophagy
-
TargetAutophagy
-
RecptorAutophagy|p38 MAPK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number444606-18-2
-
Formula Weight456.42
-
Molecular FormulaC23H19F3N4O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:125 mg/mL (273.87 mM; Need ultrasonic)
-
SMILESCc(cc(cc1)F)c1-c1c(C=CC(N2c(c(F)ccc3)c3F)=O)c2nc(NC(CO)CO)n1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Singh D, et al. A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol. 2010 Jan;50(1):94-100.
molnova catalog
related products
-
IITZ-01
IITZ-01 (Autophagy inhibitor IITZ-01) is a novel potent lysosomotropic autophagy inhibitor.
-
Graveoline
Graveoline is an apoptosis and autophagy inducer in skin melanoma cancer cells.
-
Pennogenin 3-O-beta-...
Pennogenin 3-O-beta-chacotrioside is an active component isolated from Paris polyphylla with anti-colorectal cancer activity. It modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1.
