Actein
CAS No. 18642-44-9
Actein( —— )
Catalog No. M23848 CAS No. 18642-44-9
Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
5MG | 552 | In Stock |
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10MG | 782 | In Stock |
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25MG | 1161 | In Stock |
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50MG | 1557 | In Stock |
|
100MG | Get Quote | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameActein
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NoteResearch use only, not for human use.
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Brief DescriptionActein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients.
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DescriptionActein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways involved in lipid disorders and carcinogenesis may make it a new agent for preventing and treating these major disorders, it has been shown to inhibit the proliferation of human breast cancer cells, by altering the activity of the ER IP3 receptor and Na,K-ATPase, inducing calcium release and modulating the NF-kB and MEK pathways.
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Synonyms——
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetAkt
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RecptorAkt;Apoptosis;JNK
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Research Area——
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Indication——
Chemical Information
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CAS Number18642-44-9
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Formula Weight676.9
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Molecular FormulaC37H56O11
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Purity>98% (HPLC)
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Solubility——
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SMILESC[C@H](C[C@]([C@@H]1O[C@@]11C)(O[C@@H]1O)O[C@H]1C2)[C@@H]1[C@@](C)([C@@H](C1)OC(C)=O)[C@]2(C)[C@H](CC2)[C@]1(C1)[C@@]1(CC1)[C@@H]2C(C)(C)[C@H]1O[C@@H]([C@@H]([C@H]1O)O)OC[C@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Arnicolide D
Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line.
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Miransertib
Miransertib (ARQ-092) is a potent, selective and allosteric inhibitor of Akt1/2/3 with IC50 of 5/4.5/16 nM respectively.