PTP1B-IN-2

CAS No. 1919853-46-5

PTP1B-IN-2 ( PTP1B-IN-2; PTP1B-IN-2; MDK3465 )

Catalog No. M18177 CAS No. 1919853-46-5

PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 110 In Stock
10MG 155 In Stock
25MG 312 In Stock
50MG 470 In Stock
100MG 683 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PTP1B-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).
  • Description
    MDK3465, also known as PTP1B-IN-2, is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor. MDK3465 has CAS#1919853-46-5. The last 4 digit of its CAS# is used for name.
  • Synonyms
    PTP1B-IN-2; PTP1B-IN-2; MDK3465
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Akt
  • Recptor
    PTP1B
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1919853-46-5
  • Formula Weight
    680.79
  • Molecular Formula
    C34H36N2O9S2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 100 mg/mL; 146.89 mM
  • SMILES
    CC1=CC=C(C=C1)COC2=C(C=C(C=C2)N(CC3=CC=C(C=C3)N(CC(=O)OC)S(=O)(=O)C)S(=O)(=O)CC4=CC=CC=C4)C(=O)OC
  • Chemical Name
    methyl 5-((4-((N-(4-(N-(2-methoxy-2-oxoethyl)methylsulfonamido)benzyl)-1-phenylmethyl)sulfonamido)phenoxy)methyl)-2-methylbenzoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liu P, et al. Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity. Eur J Med Chem. 2016 Aug 8;118:27-33.
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