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PTP1B-IN-2
CAS No. 1919853-46-5
PTP1B-IN-2( PTP1B-IN-2 | PTP1B-IN-2 | MDK3465 )
Catalog No. M18177 CAS No. 1919853-46-5
PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 110 | In Stock |
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| 10MG | 155 | In Stock |
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| 25MG | 312 | In Stock |
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| 50MG | 470 | In Stock |
|
| 100MG | 683 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePTP1B-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionPTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).
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DescriptionMDK3465, also known as PTP1B-IN-2, is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor. MDK3465 has CAS#1919853-46-5. The last 4 digit of its CAS# is used for name.
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In Vitro——
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In Vivo——
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SynonymsPTP1B-IN-2 | PTP1B-IN-2 | MDK3465
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetAkt
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RecptorPTP1B
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Research Area——
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Indication——
Chemical Information
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CAS Number1919853-46-5
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Formula Weight680.79
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Molecular FormulaC34H36N2O9S2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 100 mg/mL; 146.89 mM
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SMILESCC1=CC=C(C=C1)COC2=C(C=C(C=C2)N(CC3=CC=C(C=C3)N(CC(=O)OC)S(=O)(=O)C)S(=O)(=O)CC4=CC=CC=C4)C(=O)OC
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Chemical Namemethyl 5-((4-((N-(4-(N-(2-methoxy-2-oxoethyl)methylsulfonamido)benzyl)-1-phenylmethyl)sulfonamido)phenoxy)methyl)-2-methylbenzoate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Liu P, et al. Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity. Eur J Med Chem. 2016 Aug 8;118:27-33.
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