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PTP1B-IN-2

CAS No. 1919853-46-5

PTP1B-IN-2 ( PTP1B-IN-2; PTP1B-IN-2; MDK3465 )

Catalog No. M18177 CAS No. 1919853-46-5

PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 110 In Stock
10MG 155 In Stock
25MG 312 In Stock
50MG 470 In Stock
100MG 683 In Stock
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Biological Information

  • Product Name
    PTP1B-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).
  • Description
    MDK3465, also known as PTP1B-IN-2, is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor. MDK3465 has CAS#1919853-46-5. The last 4 digit of its CAS# is used for name.
  • Synonyms
    PTP1B-IN-2; PTP1B-IN-2; MDK3465
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Akt
  • Recptor
    PTP1B
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1919853-46-5
  • Formula Weight
    680.79
  • Molecular Formula
    C34H36N2O9S2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 100 mg/mL; 146.89 mM
  • SMILES
    CC1=CC=C(C=C1)COC2=C(C=C(C=C2)N(CC3=CC=C(C=C3)N(CC(=O)OC)S(=O)(=O)C)S(=O)(=O)CC4=CC=CC=C4)C(=O)OC
  • Chemical Name
    methyl 5-((4-((N-(4-(N-(2-methoxy-2-oxoethyl)methylsulfonamido)benzyl)-1-phenylmethyl)sulfonamido)phenoxy)methyl)-2-methylbenzoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liu P, et al. Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity. Eur J Med Chem. 2016 Aug 8;118:27-33.
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