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SC-66

CAS No. 871361-88-5

SC-66 ( SC66;SC 66 )

Catalog No. M16333 CAS No. 871361-88-5

SC66 is an allosteric Akt inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

SC-66
Note

Research use only, not for human use.
Brief Description

SC66 is an allosteric Akt inhibitor.
Description

SC66 is an allosteric Akt inhibitor; exhibits a dual inhibitory activity that directly interferes with the PH domain binding to PIP3 and facilitates Akt ubiquitination; has anticancer activity mouse xenograft tumor model.
Synonyms

SC66;SC 66
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

Akt
Recptor

Akt
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

871361-88-5
Formula Weight

276.33
Molecular Formula

C18H16N2O
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 34 mg/mL
SMILES

O=C1/C(CCC/C1=C\C2=CC=NC=C2)=C/C3=CC=NC=C3
Chemical Name

Cyclohexanone, 2,6-bis(4-pyridinylmethylene)-, (2E,6E)-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Jo H, et al. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6486-91.
2. Cusimano A, et al. Oncotarget. 2015 Jan 30;6(3):1707-22.

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