SC-66
CAS No. 871361-88-5
SC-66 ( SC66;SC 66 )
Catalog No. M16333 CAS No. 871361-88-5
SC66 is an allosteric Akt inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 37 | In Stock |
|
10MG | 51 | In Stock |
|
25MG | 87 | In Stock |
|
50MG | 149 | In Stock |
|
100MG | Get Quote | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSC-66
-
NoteResearch use only, not for human use.
-
Brief DescriptionSC66 is an allosteric Akt inhibitor.
-
DescriptionSC66 is an allosteric Akt inhibitor; exhibits a dual inhibitory activity that directly interferes with the PH domain binding to PIP3 and facilitates Akt ubiquitination; has anticancer activity mouse xenograft tumor model.
-
SynonymsSC66;SC 66
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetAkt
-
RecptorAkt
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number871361-88-5
-
Formula Weight276.33
-
Molecular FormulaC18H16N2O
-
Purity>98% (HPLC)
-
SolubilityDMSO: ≥ 34 mg/mL
-
SMILESO=C1/C(CCC/C1=C\C2=CC=NC=C2)=C/C3=CC=NC=C3
-
Chemical NameCyclohexanone, 2,6-bis(4-pyridinylmethylene)-, (2E,6E)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jo H, et al. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6486-91.
2. Cusimano A, et al. Oncotarget. 2015 Jan 30;6(3):1707-22.
2. Cusimano A, et al. Oncotarget. 2015 Jan 30;6(3):1707-22.
molnova catalog
related products
-
AKT Kinase Inhibitor
An Akt kinase inhibitor.
-
API-1
API-1 is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .
-
10-NCP
10-NCP (10-DEBC) is a potent neuronal autophagy inducer and increases TDP43 clearance, a reversible and specific inhibitor of Akt activity in vitro.