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Cariprazine
CAS No. 839712-12-8
Cariprazine ( RGH-188 )
Catalog No. M19163 CAS No. 839712-12-8
Cariprazine is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 65 | In Stock |
|
| 5MG | 99 | In Stock |
|
| 10MG | 170 | In Stock |
|
| 25MG | 300 | In Stock |
|
| 50MG | 447 | In Stock |
|
| 100MG | 624 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCariprazine
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NoteResearch use only, not for human use.
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Brief DescriptionCariprazine is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
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DescriptionCariprazine is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
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SynonymsRGH-188
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetAkt
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RecptorD3;D2;5-HT1A
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number839712-12-8
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Formula Weight427.41
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Molecular FormulaC21H32Cl2N4O
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Purity98%
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Solubility——
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SMILESCN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Seneca N,et al.Occupancy of dopamine D and D and serotonin 5-HTA receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography. Psychopharmacology (Berl). 2011 Dec;218(3):579-87.
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