Cart
sales@molnova.com
AN-12-H5
CAS No. 1193340-31-6
AN-12-H5( —— )
Catalog No. M10672 CAS No. 1193340-31-6
AN-12-H5 is a bifunctional, enviroxime-like anti-Enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection with EC50 of 0.55 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1229 | Get Quote |
|
| 50MG | 2507 | Get Quote |
|
| 100MG | 3168 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAN-12-H5
-
NoteResearch use only, not for human use.
-
Brief DescriptionAN-12-H5 is a bifunctional, enviroxime-like anti-Enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection with EC50 of 0.55 uM.
-
DescriptionAN-12-H5 is a bifunctional, enviroxime-like anti-Enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection with EC50 of 0.55 uM; mutations in capsid proteins (G3112A, VP1-Ala224Thr, and G2396A, VP3-Arg227Lys mutations) are resistant to AN-12-H5.
-
In VitroAN-12-H5 shows no inhibitory effect on PI4KB activity and only moderate inhibitory effects on PI 3-kinase activity.
-
In Vivo——
-
Synonyms——
-
PathwayMicrobiology/Virology
-
TargetEnterovirus
-
RecptorEnterovirus
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1193340-31-6
-
Formula Weight513.645
-
Molecular FormulaC24H23N3O4S3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (194.69 mM)
-
SMILES——
-
Chemical NameN-((6aS,8S)-2-(4-(methylthio)phenyl)-6,12-dioxo-5,6,6a,7,8,9,10,12-octahydrobenzo[e]pyrido[1,2-a][1,4]diazepin-8-yl)thiophene-2-sulfonamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Arita M, et al. J Gen Virol. 2010 Nov;91(Pt 11):2734-44.
2. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72.
3. Arita M, et al. J Virol. 2013 Apr;87(8):4252-60.
molnova catalog
related products
-
BF738735
BF738735 is a novel, broad-spectrum inhibitor of enterovirus replication (EC50=4-71 nM) that specifically targets host cell factor PI4KIIIβ with IC50 of 5.7 nM.
-
T-00127-HEV1
T-00127-HEV1 is a broad-spectrum antienterovirus compound that selectively inhibits PI4KB activity with IC50 of 60 nM.
-
Vapendavir
Vapendavir (BTA798) is a novel potent enteroviral capsid binder, inhibits EV71 replication of all isolates with mean EC50 of 0.7 uM.
