Cart
sales@molnova.com
AK-7
CAS No. 420831-40-9
AK-7 ( AK 7;AK7 )
Catalog No. M14434 CAS No. 420831-40-9
A potent, selective and brain-permeable SIRT2 inhibitor with IC50 of 15.5 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 38 | In Stock |
|
| 5MG | 61 | In Stock |
|
| 10MG | 96 | In Stock |
|
| 25MG | 177 | In Stock |
|
| 50MG | 312 | In Stock |
|
| 100MG | 512 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAK-7
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, selective and brain-permeable SIRT2 inhibitor with IC50 of 15.5 uM.
-
DescriptionA potent, selective and brain-permeable SIRT2 inhibitor with IC50 of 15.5 uM; reduces cholesterol in cultured naive neuronal cells and brain slices from wild-type mice; shows neuroprotective activity in Huntington's disease mouse models, and reduces cholesterol in neuronal models.
-
SynonymsAK 7;AK7
-
PathwayChromatin/Epigenetic
-
TargetSirtuin
-
RecptorSirtuin
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number420831-40-9
-
Formula Weight437.35
-
Molecular FormulaC19H21BrN2O3S
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESO=C(NC1=CC=CC(Br)=C1)C2=CC=CC(S(=O)(N3CCCCCC3)=O)=C2
-
Chemical NameBenzamide, N-(3-bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Taylor DM, et al. ACS Chem Biol. 2011 Jun 17;6(6):540-6.
2. Chopra V, et al. Cell Rep. 2012 Dec 27;2(6):1492-7.
3. Biella G, et al. J Alzheimers Dis. 2016 Jun 30;53(3):1193-207.
2. Chopra V, et al. Cell Rep. 2012 Dec 27;2(6):1492-7.
3. Biella G, et al. J Alzheimers Dis. 2016 Jun 30;53(3):1193-207.
molnova catalog
related products
-
OSS-128167
OSS-128167 is a novel selective, cell permeable SIRT6 inhibitor.
-
Sirt2-IN-1
Sirt2-IN-1 is a inhibitor of sirtuin 2 (Sirt2)(IC50 of 163 nM).
-
Nicotinamide
Nicotinamide (Vitamin B3), a water-soluble vitamin, is an active component of coenzymes NAD and NADP.
