10-Hydroxycampothecin

CAS No. 67656-30-8

10-Hydroxycampothecin ( 10-HCPT )

Catalog No. M19824 CAS No. 67656-30-8

10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor utilized as a clinical therapy agent against hepatoma.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 221 In Stock
10MG 319 In Stock
25MG 492 In Stock
50MG 761 In Stock
100MG 1215 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    10-Hydroxycampothecin
  • Note
    Research use only not for human use.
  • Brief Description
    10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor utilized as a clinical therapy agent against hepatoma.
  • Description
    10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor utilized as a clinical therapy agent against hepatoma.
  • Synonyms
    10-HCPT
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    Topo I
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    67656-30-8
  • Formula Weight
    364.35
  • Molecular Formula
    C20H16N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:8 mg/mL (21.95 mM) warmed;Ethanol: Insoluble;Water: Insoluble
  • SMILES
    CCC1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)cc4cc3Cn1c2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liu M et al. Intracellular delivery of 10-hydroxycamptothecin with targeted nanostructured lipid carriers against multidrug resistance. J Drug Target. 2016;24(5):433-40.
molnova catalog
related products
  • 10-Hydroxycamptothec...

    (S)-10-Hydroxycamptothecin is a clinical therapy agent against hepatoma.

  • Irinotecan hydrochlo...

    Irinotecan Hcl-trihydrate prevents DNA from unwinding by inhibition of topoisomerase 1.

  • Pirarubicin

    Pirarubicin is an anthracycline antibiotic, and also a DNA/RNA synthesis inhibitor by intercalating into Dna and interacts with topoisomerase II, used as an antineoplastic agent.