m-PEG12-OH

CAS No. 2050595-03-2

m-PEG12-OH ( Dodecaethylene Glycol Monomethyl Ether )

Catalog No. M26969 CAS No. 2050595-03-2

m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    m-PEG12-OH
  • Note
    Research use only, not for human use.
  • Brief Description
    m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
  • Synonyms
    Dodecaethylene Glycol Monomethyl Ether
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DENV NS2B-NS3 protease
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2050595-03-2
  • Formula Weight
    560.7
  • Molecular Formula
    C25H52O13
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Watowich, Stanley J, et al. SMALL-MOLECULE INHIBITORS OF DENGUE VIRUS PROTEASES. US20150141521A1.
molnova catalog
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