m-PEG12-OH

Research use only, not for human use.

m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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Dodecaethylene Glycol Monomethyl Ether

Others

Other Targets

DENV NS2B-NS3 protease

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2050595-03-2

560.67

C25H52O13

>98% (HPLC)

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COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

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(-20℃)

With Ice Pack

≥ 2 years