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icFSP1
CAS No. 1115910-36-5
icFSP1( —— )
Catalog No. M36858 CAS No. 1115910-36-5
icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 441 | In Stock |
|
| 5MG | 631 | In Stock |
|
| 10MG | 884 | In Stock |
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| 25MG | 1205 | In Stock |
|
| 50MG | 1509 | In Stock |
|
| 100MG | 1796 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameicFSP1
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NoteResearch use only, not for human use.
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Brief DescriptionicFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.
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DescriptionicFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number1115910-36-5
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Formula Weight459.49
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Molecular FormulaC26H25N3O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (217.63 mM; Ultrasonic )
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SMILESO=C1N(C(C)=NC=2C1=CC=CC2)C3=CC=C(NC(CC4=CC(OC)=C(OC)C(OC)=C4)=O)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Toshitaka Nakamura, et al. Phase separation of FSP1 promotes ferroptosis. Nature. 2023 Jul;619(7969):371-377.?
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