afamelanotide ( —— )

Catalog No. M20799 CAS No. 1566590-77-9

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Product Name

afamelanotide
Note

Research use only not for human use.
Brief Description

Afamelanotide is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist used to?for Erythropoietic Protoporphyria.
Description

Afamelanotide is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist used to?for Erythropoietic Protoporphyria.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Metabolic Disease
Indication

erythropoietic protoporphyria?

CAS Number

1566590-77-9
Formula Weight

1706.9
Molecular Formula

C80H115N21O21
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(O)=O.CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
Chemical Name

——

1.Langendonk J G Balwani M Anderson K E et al. Afamelanotide for Erythropoietic Protoporphyria[J]. New England Journal of Medicine 2015 373(1):48-59.

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