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JNJ-26489112
CAS No. 871824-55-4
JNJ-26489112 ( JNJ26489112 )
Catalog No. M16338 CAS No. 871824-55-4
JNJ-26489112 (JNJ26489112) is a broad-spectrum anticonvulsant that displays activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameJNJ-26489112
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NoteResearch use only, not for human use.
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Brief DescriptionJNJ-26489112 (JNJ26489112) is a broad-spectrum anticonvulsant that displays activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures.
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DescriptionJNJ-26489112 (JNJ26489112) is a broad-spectrum anticonvulsant that displays activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures; exhibits very weak inhibition of human CA-II (IC50=35 μM); inhibits Na+, kainate, and KCNQ2 channels to varying degrees, while moderately potentiating GABA current and inhibiting N-methyl-D-aspartic acid current, its action at several targets appears to be responsible for the observed neurostabilizing effects; shows limited seizure spread and elevated seizure threshold in preclinical animal models.Epilepsy Discontinued
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SynonymsJNJ26489112
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaNeurological Disease
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IndicationEpilepsy
Chemical Information
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CAS Number871824-55-4
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Formula Weight278.71
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Molecular FormulaC9H11ClN2O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(NC[C@@H]1OC2=CC=C(Cl)C=C2OC1)(N)=O
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Chemical Name(S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. McComsey DF, et al. J Med Chem. 2013 Nov 27;56(22):9019-30.
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