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ZL0580
CAS No. 2377151-10-3
ZL0580 ( —— )
Catalog No. M24093 CAS No. 2377151-10-3
ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 49 | In Stock |
|
| 5MG | 80 | In Stock |
|
| 10MG | 140 | In Stock |
|
| 25MG | 259 | In Stock |
|
| 50MG | 383 | In Stock |
|
| 100MG | 565 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameZL0580
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NoteResearch use only, not for human use.
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Brief DescriptionZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter.
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DescriptionZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter.
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetEpigenetic Reader Domain
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RecptorBRD4;HIV
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Research Area——
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Indication——
Chemical Information
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CAS Number2377151-10-3
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Formula Weight532.5
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Molecular FormulaC25H23F3N4O4S
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Purity>98% (HPLC)
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SolubilityDMSO:250 mg/mL (469.46 mM; Need ultrasonic)
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SMILESC1C[C@H](N(C1)S(=O)(=O)C2=CC=C(C=C2)NC(=O)NC3=CC=C(C=C3)C(F)(F)F)C(=O)NC4=CC=CC=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Niu Q, et al. Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV. J Clin Invest. 2019 Jul 22;129(8):3361-3373.
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