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ZD-7288
CAS No. 133059-99-1
ZD-7288( ICI-D 7288 )
Catalog No. M11314 CAS No. 133059-99-1
ZD-7288 (ICI-D 7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 27 | In Stock |
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| 5MG | 43 | In Stock |
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| 10MG | 76 | In Stock |
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| 25MG | 173 | In Stock |
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| 50MG | 324 | In Stock |
|
| 100MG | 482 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameZD-7288
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NoteResearch use only, not for human use.
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Brief DescriptionZD-7288 (ICI-D 7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.
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DescriptionZD-7288 (ICI-D 7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker; inhibits the hyperpolarization activated cationic current (If) in a concentration-dependent manner in rat brain.Heart Arrhythmia Phase 2 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsICI-D 7288
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PathwayMembrane Transporter/Ion Channel
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TargetHCN Channel
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RecptorHCN Channel
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Research AreaCardiovascular Disease
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IndicationHeart Arrhythmia
Chemical Information
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CAS Number133059-99-1
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Formula Weight292.81
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Molecular FormulaC15H21ClN4
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Purity>98% (HPLC)
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SolubilityDMSO : 50 mg/mL 170.76 mM; H2O : ≥ 50 mg/mL 170.76 mM
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SMILESC/N=C1C=C(N(CC)C2=CC=CC=C2)N=C(C)N/1C
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Chemical Name(Z)-N-ethyl-1,2-dimethyl-6-(methylimino)-N-phenyl-1,6-dihydropyrimidin-4-amine hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang XX, et al. Neural Regen Res. 2016 May;11(5):779-86.
2. Guli X, et al. Neural Plast. 2012;2012:237913.
3. BoSmith RE, et al. Br J Pharmacol. 1993 Sep;110(1):343-9.
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