Cart
sales@molnova.com
Home - Products - Microbiology/Virology - HIV - YLC2-155

YLC2-155

CAS No. 1354742-60-1

YLC2-155 ( YLC 2-155;YLC2155 )

Catalog No. M11447 CAS No. 1354742-60-1

YLC2-155 is a novel potent HIV-1 reverse transcriptase (RT) inhibitor that inhibits both polymerase (IC50=2.6 uM) and RNase H function (IC50=0.65 uM) of RT.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    YLC2-155
  • Note
    Research use only, not for human use.
  • Brief Description
    YLC2-155 is a novel potent HIV-1 reverse transcriptase (RT) inhibitor that inhibits both polymerase (IC50=2.6 uM) and RNase H function (IC50=0.65 uM) of RT.
  • Description
    YLC2-155 is a novel potent HIV-1 reverse transcriptase (RT) inhibitor that inhibits both polymerase (IC50=2.6 uM) and RNase H function (IC50=0.65 uM) of RT; binds at the RNase H (RNH)-active site in multiple conformations; demonstrates inhibition of fully infectious HIV-1 (strain NL4-3) with EC50 of 6.7 uM in cell-based assays.
  • Synonyms
    YLC 2-155;YLC2155
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1354742-60-1
  • Formula Weight
    243.22
  • Molecular Formula
    C13H9NO4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    7-(furan-2-yl)-2-hydroxyisoquinoline-1,3(2H,4H)-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kirby KA, et al. Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e01351-17.
2. Kirby KA, et al. Antimicrob Agents Chemother. 2012 Apr;56(4):2048-61.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • HIV-1 inhibitor 5b

    HIV-1 inhibitor 5b is a novel anti-HIV-1 compound that inhibits HIV-1 JR-CSF with EC50 of 1 nM without significant cytotoxicity (CC50>20 uM).

  • BMS-538203

    A chemical intermidate of BMS-626529, a HIV-1 attachment inhibitor that targets gp120,

  • BI 224436

    BI 224436 is a potent, specific, noncatalytic site integrase inhibitor (NCINI) of HIV-1 with EC50 of 11-27 nM against different HIV-1 laboratory strains.

Sign In Join Free