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YLC2-155
CAS No. 1354742-60-1
YLC2-155( YLC 2-155 | YLC2155 )
Catalog No. M11447 CAS No. 1354742-60-1
YLC2-155 is a novel potent HIV-1 reverse transcriptase (RT) inhibitor that inhibits both polymerase (IC50=2.6 uM) and RNase H function (IC50=0.65 uM) of RT.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameYLC2-155
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NoteResearch use only, not for human use.
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Brief DescriptionYLC2-155 is a novel potent HIV-1 reverse transcriptase (RT) inhibitor that inhibits both polymerase (IC50=2.6 uM) and RNase H function (IC50=0.65 uM) of RT.
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DescriptionYLC2-155 is a novel potent HIV-1 reverse transcriptase (RT) inhibitor that inhibits both polymerase (IC50=2.6 uM) and RNase H function (IC50=0.65 uM) of RT; binds at the RNase H (RNH)-active site in multiple conformations; demonstrates inhibition of fully infectious HIV-1 (strain NL4-3) with EC50 of 6.7 uM in cell-based assays.
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In Vitro——
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In Vivo——
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SynonymsYLC 2-155 | YLC2155
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research Area——
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Indication——
Chemical Information
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CAS Number1354742-60-1
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Formula Weight243.22
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Molecular FormulaC13H9NO4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name7-(furan-2-yl)-2-hydroxyisoquinoline-1,3(2H,4H)-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kirby KA, et al. Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e01351-17.
2. Kirby KA, et al. Antimicrob Agents Chemother. 2012 Apr;56(4):2048-61.
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