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CX 04328

CAS No. 957890-42-5

CX 04328( LEDGIN-6 )

Catalog No. M16841 CAS No. 957890-42-5

CX 04328 (LEDGIN-6) is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 1.37 uM.

Purity : >98% (HPLC)

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HNMR

HPLC

MSDS

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Biological Information

Product Name

CX 04328
Note

Research use only, not for human use.
Brief Description

CX 04328 (LEDGIN-6) is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 1.37 uM.
Description

CX 04328 (LEDGIN-6) is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 1.37 uM, antiviral activity EC50 of 2.35 uM.
In Vitro

——
In Vivo

——
Synonyms

LEDGIN-6
Pathway

Microbiology/Virology
Target

HIV
Recptor

HIV
Research Area

Infection
Indication

——

Chemical Information

CAS Number

957890-42-5
Formula Weight

353.846
Molecular Formula

C21H20ClNO2
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 100 mg/mL 282.61 mM; H2O : < 0.1 mg/mL
SMILES

CCCC(C1=C(C2=CC=CC=C2)C3=CC(Cl)=CC=C3N=C1C)C(O)=O
Chemical Name

2-(6-chloro-2-methyl-4-phenylquinolin-3-yl)pentanoic acid

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Christ F, et al. Nat Chem Biol. 2010 Jun;6(6):442-8.

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