YIR-819
CAS No. 1883372-86-8
YIR-819( YIR819 )
Catalog No. M12922 CAS No. 1883372-86-8
YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor.
YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
100MG | Get Quote | Get Quote |
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200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameYIR-819
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NoteResearch use only, not for human use.
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Brief DescriptionYIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor.
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DescriptionYIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS.
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In Vitro——
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In Vivo——
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SynonymsYIR819
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research Area——
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Indication——
Chemical Information
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CAS Number1883372-86-8
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Formula Weight492.021
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Molecular FormulaC23H34ClN7O3
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN1-(4-chlorophenyl)-N2-(1-(2-(2-guanidinoacetamido)ethyl)-1-azaspiro[5.5]undecan-4-yl)oxalamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Helichrysetin
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.Searching for anti-HIV-1 protease (PR) inhibitors of Thai medicinal plants led to the isolation of a new cyclohexenyl chalcone named panduratin C and chalcone derivatives (2-6) from the methanol extract of Boesenbergia pandurata rhizomes.
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TAT 48-57
TAT (48-57) is a cell-permeable peptide, derived from HIV-1 transactivator of transcription (Tat) protein residue 48-57.This peptide is amino acid residues 48 to 57 fragment of the basic domain of HIV Tat.
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Astrasieversianin VI...
Isoastragaloside II is a derivative Astragaloside I, an ingredient in Astragalus membranaceus which is reported to have osteogenic properties.