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Home - Products - Chromatin/Epigenetic - Epigenetic Reader Domain - Y06036

Y06036

CAS No. 1832671-96-1

Y06036 ( —— )

Catalog No. M20086 CAS No. 1832671-96-1

Y06036 a potent and selective BET inhibitor can bind to the BRD4(1) bromodomain (Kd: 82 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 58 In Stock
25MG 110 In Stock
50MG 178 In Stock
100MG 332 In Stock
500MG 782 In Stock
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Biological Information

  • Product Name
    Y06036
  • Note
    Research use only not for human use.
  • Brief Description
    Y06036 a potent and selective BET inhibitor can bind to the BRD4(1) bromodomain (Kd: 82 nM).
  • Description
    Y06036 a potent and selective BET inhibitor can bind to the BRD4(1) bromodomain (Kd: 82 nM).
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Epigenetic Reader Domain
  • Recptor
    BRD4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1832671-96-1
  • Formula Weight
    427.27
  • Molecular Formula
    C16H15BrN2O5S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mg/mL (234 mM)
  • SMILES
    COc1ccc(Br)cc1S(=O)(=O)Nc1cc2c(C)noc2cc1OC
  • Chemical Name
    5-Bromo-2-methoxy-N-(6-methoxy-3-methylbenzo[d]-isoxazol-5-yl)benzenesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang M et al. Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC). J Med Chem. 2018 Apr 12;61(7):3037-3058.
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