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RVX-208
CAS No. 1044870-39-4
RVX-208 ( RVX208; RVX 208; RVX-208; Apabetalone )
Catalog No. M10222 CAS No. 1044870-39-4
RVX-208 is a potent BET bromodomain inhibitor with IC50 of 0.510 μM for BD2 in a cell-free assay, about 170-fold selectivity over BD1. Phase 2.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 35 | In Stock |
|
| 25MG | 65 | In Stock |
|
| 50MG | 107 | In Stock |
|
| 100MG | 156 | In Stock |
|
| 500MG | 386 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRVX-208
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NoteResearch use only, not for human use.
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Brief DescriptionRVX-208 is a potent BET bromodomain inhibitor with IC50 of 0.510 μM for BD2 in a cell-free assay, about 170-fold selectivity over BD1. Phase 2.
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DescriptionRVX-208 is a potent BET bromodomain inhibitor with IC50 of 0.510 μM for BD2 in a cell-free assay, about 170-fold selectivity over BD1. Phase 2.
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SynonymsRVX208; RVX 208; RVX-208; Apabetalone
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PathwayChromatin/Epigenetic
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TargetEpigenetic Reader Domain
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RecptorBD2
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number1044870-39-4
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Formula Weight370.40
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Molecular FormulaC20H22N2O5
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Purity>98%(HPLC)
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SolubilityDMSO: 74 mg/mL (199.78 mM)
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SMILESO=C1NC(C2=CC(C)=C(OCCO)C(C)=C2)=NC3=C1C(OC)=CC(OC)=C3
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Chemical Name2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Picaud S, et al. Proc Natl Acad Sci U S A. 2013, 110(49), 19754-19759.
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