Cart
sales@molnova.com
Home - Products - Chromatin/Epigenetic - Epigenetic Reader Domain - RVX-208

RVX-208

CAS No. 1044870-39-4

RVX-208 ( RVX208; RVX 208; RVX-208; Apabetalone )

Catalog No. M10222 CAS No. 1044870-39-4

RVX-208 is a potent BET bromodomain inhibitor with IC50 of 0.510 μM for BD2 in a cell-free assay, about 170-fold selectivity over BD1. Phase 2.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 35 In Stock
25MG 65 In Stock
50MG 107 In Stock
100MG 156 In Stock
500MG 386 In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    RVX-208
  • Note
    Research use only, not for human use.
  • Brief Description
    RVX-208 is a potent BET bromodomain inhibitor with IC50 of 0.510 μM for BD2 in a cell-free assay, about 170-fold selectivity over BD1. Phase 2.
  • Description
    RVX-208 is a potent BET bromodomain inhibitor with IC50 of 0.510 μM for BD2 in a cell-free assay, about 170-fold selectivity over BD1. Phase 2.
  • Synonyms
    RVX208; RVX 208; RVX-208; Apabetalone
  • Pathway
    Chromatin/Epigenetic
  • Target
    Epigenetic Reader Domain
  • Recptor
    BD2
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    1044870-39-4
  • Formula Weight
    370.40
  • Molecular Formula
    C20H22N2O5
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 74 mg/mL (199.78 mM)
  • SMILES
    O=C1NC(C2=CC(C)=C(OCCO)C(C)=C2)=NC3=C1C(OC)=CC(OC)=C3
  • Chemical Name
    2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Picaud S, et al. Proc Natl Acad Sci U S A. 2013, 110(49), 19754-19759.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • SGC-SMARCA-BRDVIII

    SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM, respectively.

  • PFI-1

    PFI-1 is a selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM in a cell-free assay.

  • Menin-MLL inhibitor ...

    Menin-MLL inhibitor 20 is an irreversible menin-MLL interaction inhibitor with antitumor activities (WO2020142557A1, compound 6).

Sign In Join Free