XEN723

CAS No. 1072803-08-7

XEN723 ( —— )

Catalog No. M23280 CAS No. 1072803-08-7

XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 177 In Stock
10MG 282 In Stock
25MG 480 In Stock
50MG 691 In Stock
100MG 972 In Stock
500MG 1944 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    XEN723
  • Note
    Research use only, not for human use.
  • Brief Description
    XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor.
  • Description
    XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    SCD1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1072803-08-7
  • Formula Weight
    425.5
  • Molecular Formula
    C21H20FN5O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (235.03 mM; Need ultrasonic)
  • SMILES
    Cc1c(C(NCc2cnccc2)=O)sc(N(CCN2Cc(cc3)ccc3F)C2=O)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sun S, et al. Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases. Bioorg Med Chem Lett. 2014 Jan 15;24(2):520-5.
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