WAY-100635

Research use only, not for human use.

A potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.

A potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor; completely prevents not only the hyperpolarization, with an IC50 of 1.3 nM, but also the decrease in membrane input resistance produced by 5-HT and 5-carboxamidotryptamine with IC50 of 22.5 μM and 50 nM, respectively. Anxiety Phase 1 Discontinued

WAY 100635;WAY100635

Endocrinology/Hormones

5-HT Receptor

5-HT Receptor

Neurological Disease

Anxiety

162760-96-5

422.56

C25H34N4O2

>98% (HPLC)

10 mM in DMSO

O=C(C1CCCCC1)N(CCN2CCN(C3=CC=CC=C3OC)CC2)C4=NC=CC=C4

N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)cyclohexanecarboxamide

(-20℃)

With Ice Pack

≥ 2 years