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WAY-100635
CAS No. 162760-96-5
WAY-100635 ( WAY 100635;WAY100635 )
Catalog No. M12413 CAS No. 162760-96-5
A potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 53 | Get Quote |
|
| 50MG | 320 | Get Quote |
|
| 100MG | 566 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameWAY-100635
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NoteResearch use only, not for human use.
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Brief DescriptionA potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
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DescriptionA potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor; completely prevents not only the hyperpolarization, with an IC50 of 1.3 nM, but also the decrease in membrane input resistance produced by 5-HT and 5-carboxamidotryptamine with IC50 of 22.5 μM and 50 nM, respectively. Anxiety Phase 1 Discontinued
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SynonymsWAY 100635;WAY100635
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaNeurological Disease
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IndicationAnxiety
Chemical Information
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CAS Number162760-96-5
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Formula Weight422.56
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Molecular FormulaC25H34N4O2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(C1CCCCC1)N(CCN2CCN(C3=CC=CC=C3OC)CC2)C4=NC=CC=C4
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Chemical NameN-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)cyclohexanecarboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Corradetti R, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):679-88.
2. Fornal CA, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):752-62.
3. García G, et al. Eur J Med Chem. 2014 Oct 6;85:795-806.
2. Fornal CA, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):752-62.
3. García G, et al. Eur J Med Chem. 2014 Oct 6;85:795-806.
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