Cart
sales@molnova.com
Home - Products - Chromatin/Epigenetic - Histone Demethylase - Vafidemstat

Vafidemstat

CAS No. 1357362-02-7

Vafidemstat( ORY 2001 | ORY-2001 | ORY2001 | Vafidemstat )

Catalog No. M11465 CAS No. 1357362-02-7

Vafidemstat is a novel potent, selective lysine-specific histone demethylase (LSD1) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 410 Get Quote
50MG 1449 Get Quote
100MG 2196 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Vafidemstat
  • Note
    Research use only, not for human use.
  • Brief Description
    Vafidemstat is a novel potent, selective lysine-specific histone demethylase (LSD1) inhibitor.
  • Description
    Vafidemstat is a novel potent, selective lysine-specific histone demethylase (LSD1) inhibitor.
  • In Vitro
    Vafidemstat (ORY-2001), a dual LSD1/MAO-B inhibitor, is a novel epigenetic agent for the treatment of neurodegenerative diseases. LSD1 is a protein that participates in transcription regulation complexes; its modulation can be used to tweak transcriptional imbalances in neurodegenerative disease and redress neuroinflammation and cognitive deficit. Vafidemstat (ORY-2001) can be used in the treatment of Alzheimer's disease.
  • In Vivo
    ——
  • Synonyms
    ORY 2001 | ORY-2001 | ORY2001 | Vafidemstat
  • Pathway
    Chromatin/Epigenetic
  • Target
    Histone Demethylase
  • Recptor
    Histone Demethylase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1357362-02-7
  • Formula Weight
    336.395
  • Molecular Formula
    C19H20N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (148.64 mM)
  • SMILES
    [H][C@@]1([C@@](NCC2=NN=C(N)O2)([H])C1)C(C=C3)=CC=C3OCC4=CC=CC=C4
  • Chemical Name
    1,3,4-Oxadiazole-2-methanamine, 5-amino-N-[(1R,2S)-2-[4-(phenylmethoxy)phenyl]cyclopropyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • OG-L002

    OG-L002 is a novel selective LSD1 inhibitor with IC50 of 20 nM.

  • KDM1A-IN-29

    KDM1A-IN-29 is a histone demethylase inhibitor.

  • MRTX-1719

    MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC 50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells.

Sign In Join Free