Cart
sales@molnova.com
Home - Products - Chromatin/Epigenetic - Histone Demethylase - MRTX-1719

MRTX-1719

CAS No. 2630904-45-7

MRTX-1719( —— )

Catalog No. M28288 CAS No. 2630904-45-7

MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC 50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 1611 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    MRTX-1719
  • Note
    Research use only, not for human use.
  • Brief Description
    MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC 50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells.
  • Description
    MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC 50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Histone Demethylase
  • Recptor
    5-HT2|D2 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2630904-45-7
  • Formula Weight
    464.88
  • Molecular Formula
    C23H18ClFN6O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (215.11 mM)
  • SMILES
    N#CC1=C(OC2CC2)C=C(Cl)C(F)=C1C3=C(C4=CC5=C(C(NN=C5CN)=O)C=C4)C=NN3C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kjellberg B, et, al. Partial restoration by a neuroleptic (spiramide) of items of grooming behaviour suppressed by amphetamine. Arch Int Pharmacodyn Ther. 1974 Jul;210(1):61-6.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Zavondemstat

    Zavondemstat (QC8222 free base) is a histone lysine demethylase 4 (KDM4) inhibitor with anticancer and antitumor activity for the study of triple-negative and breast cancers.

  • SD-70

    A small molecule tumor translocation inhibitor that inhibits the prostate cancer cell transcriptional program.

  • CCI 007

    CCI 007 is a selective inhibitor of MLL-r, CALM-AF10 and SET-NUP214 leukemia with IC50 of 3.5 uM against MLL-r leukemia cell line PER-485

Sign In Join Free