VUT-MK142
CAS No. 1313491-22-3
VUT-MK142 ( —— )
Catalog No. M22884 CAS No. 1313491-22-3
VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.VUT-MK142 was identified as the most promising candidate with respect to cardiomyogenic activity.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 106 | Get Quote |
|
5MG | 177 | Get Quote |
|
10MG | 267 | Get Quote |
|
25MG | 537 | Get Quote |
|
50MG | 745 | Get Quote |
|
100MG | 1035 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameVUT-MK142
-
NoteResearch use only, not for human use.
-
Brief DescriptionVUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.VUT-MK142 was identified as the most promising candidate with respect to cardiomyogenic activity.?
-
DescriptionVUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.VUT-MK142 was identified as the most promising candidate with respect to cardiomyogenic activity.?Treatment using this novel agent induced the strongest up-regulation of expression of the cardiac marker ANF in both P19 embryonic carcinoma cells and C2C12 skeletal myoblasts.?The activity of VUT-MK142 on this marker superseded CgC;?moreover, the novel compound significantly up-regulated the expression of other cardiac markers, and promoted the development of beating cardiomyocytes from cardiovascular progenitor cells.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1313491-22-3
-
Formula Weight298.4
-
Molecular FormulaC17H22N4O
-
Purity>98% (HPLC)
-
SolubilityDMSO:25 mg/mL (83.79 mM; Need ultrasonic)
-
SMILESCOC1=CC=C(NC2=CC(NC3CCCCC3)=NC=N2)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Moumita Koley, et al. VUT-MK142 : a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes. Medchemcomm. 2013 Aug 1;4(8):1189-1195.
molnova catalog
related products
-
Peucenidin
Peucenidin is a natural product for research related to life sciences.
-
Cuminaldehyde
Cuminaldehyde is a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity.?Cuminaldehyde shows anticancer activitywith a pleasant smell and contributes to the aroma of essential oils.
-
{Val1}-Exendin-3/4
{Val1}- exendin-3/4 is the first n-terminal 1-28 residue of exendin-4 peptide.