VUT-MK142
CAS No. 1313491-22-3
VUT-MK142 ( —— )
Catalog No. M22884 CAS No. 1313491-22-3
VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.VUT-MK142 was identified as the most promising candidate with respect to cardiomyogenic activity.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 106 | Get Quote |
|
5MG | 177 | Get Quote |
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10MG | 267 | Get Quote |
|
25MG | 537 | Get Quote |
|
50MG | 745 | Get Quote |
|
100MG | 1035 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameVUT-MK142
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NoteResearch use only, not for human use.
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Brief DescriptionVUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.VUT-MK142 was identified as the most promising candidate with respect to cardiomyogenic activity.?
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DescriptionVUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.VUT-MK142 was identified as the most promising candidate with respect to cardiomyogenic activity.?Treatment using this novel agent induced the strongest up-regulation of expression of the cardiac marker ANF in both P19 embryonic carcinoma cells and C2C12 skeletal myoblasts.?The activity of VUT-MK142 on this marker superseded CgC;?moreover, the novel compound significantly up-regulated the expression of other cardiac markers, and promoted the development of beating cardiomyocytes from cardiovascular progenitor cells.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1313491-22-3
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Formula Weight298.4
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Molecular FormulaC17H22N4O
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Purity>98% (HPLC)
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SolubilityDMSO:25 mg/mL (83.79 mM; Need ultrasonic)
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SMILESCOC1=CC=C(NC2=CC(NC3CCCCC3)=NC=N2)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Moumita Koley, et al. VUT-MK142 : a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes. Medchemcomm. 2013 Aug 1;4(8):1189-1195.
molnova catalog
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