VBIT-4

CAS No. 2086257-77-2

VBIT-4 ( VBIT-4 | VBIT 4 | VBIT4 )

Catalog No. M19386 CAS No. 2086257-77-2

VBIT-4 is an inhibitor of VDAC1 the outer mitochondrial membrane protein known as voltage-dependent anion channel 1. VBIT-4 inhibits VDAC1 oligomerization apoptosis and mitochondrial dysfunction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 218 In Stock
10MG 345 In Stock
25MG 655 In Stock
50MG 884 In Stock
100MG 1215 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    VBIT-4
  • Note
    Research use only, not for human use.
  • Brief Description
    VBIT-4 is an inhibitor of VDAC1 the outer mitochondrial membrane protein known as voltage-dependent anion channel 1. VBIT-4 inhibits VDAC1 oligomerization apoptosis and mitochondrial dysfunction.
  • Description
    VBIT-4 is an inhibitor of VDAC1 the outer mitochondrial membrane protein known as voltage-dependent anion channel 1. VBIT-4 inhibits VDAC1 oligomerization apoptosis and mitochondrial dysfunction.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    VBIT-4 | VBIT 4 | VBIT4
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Other Targets
  • Recptor
    Kd: 17 μM (VDAC1)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2086257-77-2
  • Formula Weight
    457.88
  • Molecular Formula
    C21H23ClF3N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 125 mg/mL (273.00 mM; Need ultrasonic)
  • SMILES
    OCC(N1CCN(C2=CC=C(OC(F)(F)F)C=C2)CC1)CC(NC3=CC=C(Cl)C=C3)=O
  • Chemical Name
    N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1: Ben-Hail D et al. J Biol Chem. 2016 Nov 25;291(48):24986-25003. Epub 2016 Oct 13. PubMed PMID: 27738100; PubMed Central PMCID: PMC5122769.
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