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Seneciphylline
CAS No. 480-81-9
Seneciphylline( —— )
Catalog No. M21774 CAS No. 480-81-9
Seneciphylline is a toxic pyrrolizidine alkaloid in Senecio plants. Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 249 | In Stock |
|
| 10MG | 426 | In Stock |
|
| 25MG | 683 | In Stock |
|
| 50MG | 888 | In Stock |
|
| 100MG | 1242 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSeneciphylline
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NoteResearch use only, not for human use.
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Brief DescriptionSeneciphylline is a toxic pyrrolizidine alkaloid in Senecio plants. Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities.
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DescriptionSeneciphylline is a toxic pyrrolizidine alkaloid in Senecio plants. Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number480-81-9
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Formula Weight333.38
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Molecular FormulaC??H??NO?
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 7.69 mg/mL (23.07 mM)
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SMILESO=C(O[C@]1([H])CCN2[C@]1([H])C(COC([C@](C)(O)C(C/3)=C)=O)=CC2)C3=C/C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bandyopadhyay S, et al. Cytotoxicity of Senecio in macrophages is mediated via its induction of oxidative stress. Res Vet Sci. 2009 Aug;87(1):85-90.
2. Kakrani HK, et al. Effect of seneciphylline and senecionine on hepatic drug metabolizing enzymes in rats. J Ethnopharmacol. 1984 Dec;12(3):271-8.
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