Ubiquitination-IN-1( —— )

Catalog No. M26494 CAS No. 1819330-15-8

Ubiquitination-IN-1 is an inhibitor of ubiquitination and Cksl-Skp2 protein-protein interaction (IC50: 0.17 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Ubiquitination-IN-1
Note

Research use only, not for human use.
Brief Description

Ubiquitination-IN-1 is an inhibitor of ubiquitination and Cksl-Skp2 protein-protein interaction (IC50: 0.17 μM).
Description

Ubiquitination-IN-1 is an inhibitor of ubiquitination and Cksl-Skp2 protein-protein interaction (IC50: 0.17 μM).(In Vitro):Ubiquitination-IN-1 inhibits A549 and HT1080 cells (IC50s: 0.91 and 0.4 μM).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Pim2
Research Area

——
Indication

——

Chemical Information

CAS Number

1819330-15-8
Formula Weight

429.42
Molecular Formula

C21H14F3N3O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 83.33 mg/mL (194.06 mM)
SMILES

FC(F)(F)c1cccc(c1)S(=O)(=O)Nc1ccc(-c2cccnc2)c2cccnc12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Zhao YQ, Yin YQ, Liu J, Wang GH, Huang J, Zhu LJ, Wang JH. Characterization of HJ-PI01 as a novel Pim-2 inhibitor that induces apoptosis and autophagic cell death in triple-negative human breast cancer. Acta Pharmacol Sin. 2016 Sep;37(9):1237-50.

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