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Ubiquitination-IN-1

CAS No. 1819330-15-8

Ubiquitination-IN-1 ( —— )

Catalog No. M26494 CAS No. 1819330-15-8

Ubiquitination-IN-1 is an inhibitor of ubiquitination and Cksl-Skp2 protein-protein interaction (IC50: 0.17 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ubiquitination-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    Ubiquitination-IN-1 is an inhibitor of ubiquitination and Cksl-Skp2 protein-protein interaction (IC50: 0.17 μM).
  • Description
    Ubiquitination-IN-1 is an inhibitor of ubiquitination and Cksl-Skp2 protein-protein interaction (IC50: 0.17 μM).(In Vitro):Ubiquitination-IN-1 inhibits A549 and HT1080 cells (IC50s: 0.91 and 0.4 μM).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Pim2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1819330-15-8
  • Formula Weight
    429.4
  • Molecular Formula
    C21H14F3N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    FC(F)(F)c1cccc(c1)S(=O)(=O)Nc1ccc(-c2cccnc2)c2cccnc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhao YQ, Yin YQ, Liu J, Wang GH, Huang J, Zhu LJ, Wang JH. Characterization of HJ-PI01 as a novel Pim-2 inhibitor that induces apoptosis and autophagic cell death in triple-negative human breast cancer. Acta Pharmacol Sin. 2016 Sep;37(9):1237-50.
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