FH1

Research use only, not for human use.

FH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.

FH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.

FH1 (NSC 12407, 5 μg/mL, 0-40 days) enhances hepatic maturation and maintain the hepatic differentiation state of hiPSC-HLCs. RT-PCRCell Line:hiPSC-HLCs in the differentiated hepatic state.Concentration:5 μg/mL.Incubation Time:0-40 days.Result:Kept more than 50% hiPSC-HLCs to produce the four factors till day 40.Can help hiPSC-HLCs to maintain a relatively mature hepatic differentiation state for about 40 days.Maintained a higher level of hALB in the supernatant than that in controls.Maintained relatively high mRNA levels of hNTCP, hRXR, hHNF4α, and hALB for over functional small molecule FH1 can help hiPSC-HLCs to maintain a relatively mature hepatic differentiation state for about 40 days.

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BRD-K4477

Others

Other Targets

iPS-derived hepatocytes

Other Indications

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2719-05-3

282.34

C17H18N2O2

>98% (HPLC)

DMSO: 56 mg/mL (198.34 mM)

CC(=O)NC1=CC=C(CC2=CC=C(NC(C)=O)C=C2)C=C1

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(-20℃)

With Ice Pack

≥ 2 years