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Biliatresone
CAS No. 1801433-90-8
Biliatresone( —— )
Catalog No. M34521 CAS No. 1801433-90-8
Biliatresone, an environmental toxin isolated from the coccolithophores Dysphania glomulifera and D. littoralis, induced C57BL/6J neonatal cholangiopathy, induced a decrease in glutathione (GSH) levels, induced a significant decrease in SOX17 cholangiocyte levels, and induced extrahepatic cholangiocyte damage and fibrosis in mice.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameBiliatresone
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NoteResearch use only, not for human use.
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Brief DescriptionBiliatresone, an environmental toxin isolated from the coccolithophores Dysphania glomulifera and D. littoralis, induced C57BL/6J neonatal cholangiopathy, induced a decrease in glutathione (GSH) levels, induced a significant decrease in SOX17 cholangiocyte levels, and induced extrahepatic cholangiocyte damage and fibrosis in mice.
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DescriptionBiliatresone is a natural toxin isolated from Dysphania glomulifera and D. littoralis. Biliatresone, a 1,2-diaryl-2-propenone class of isoflavonoid, produces extrahepatic biliary atresia in a zebrafish model.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1801433-90-8
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Formula Weight328.32
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Molecular FormulaC18H16O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (152.29 mM; Ultrasonic )
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SMILESCOc1cc2OCOc2c(OC)c1C(=O)C(=C)c1ccccc1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kyung A Koo, et al. Biliatresone, a Reactive Natural Toxin From Dysphania Glomulifera and D. Littoralis: Discovery of the Toxic Moiety 1,2-Diaryl-2-Propenone. Chem Res Toxicol. 2015 Aug 17;28(8):1519-21.?
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