Cart
sales@molnova.com
Home - Products - Tyrosine Kinase - TAM Receptor - UNC2541

UNC2541

CAS No. 1612782-86-1

UNC2541 ( —— )

Catalog No. M23714 CAS No. 1612782-86-1

UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 38 In Stock
5MG 61 In Stock
10MG 98 In Stock
25MG 210 In Stock
50MG 314 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    UNC2541
  • Note
    Research use only, not for human use.
  • Brief Description
    UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM).
  • Description
    UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).
  • Synonyms
    ——
  • Pathway
    Tyrosine Kinase
  • Target
    TAM Receptor
  • Recptor
    Axl;Flt3;pMerTK;Tyro3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1612782-86-1
  • Formula Weight
    471.6
  • Molecular Formula
    C24H34FN7O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mg/mL (21.21 mM; ultrasonic and warming and heat to 60°C)
  • SMILES
    C1CCCNC2=NC=C(C(=N2)NCCCC[C@@H](C(=O)NCC1)N)C(=O)NCC3=CC=C(C=C3)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.McIver AL, et al. Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors. ChemMedChem. 2017 Feb 3;12(3):207-213.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Sodium Picosulfate

    Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.

  • S49076

    S49076 is a potent, ATP-competitive tyrosine kinase inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 of <20 nM.

  • RU-302

    RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain.

Sign In Join Free