UNC2250( UNC2250, UNC-2250, UNC 2250 )

Catalog No. M12068 CAS No. 1493694-70-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

UNC2250
Note

Research use only, not for human use.
Brief Description

UNC2250 is a potent and selective Mer inhibitor with IC50 of 1.7 nM, about 160- and 60-fold selectivity over the closely related kinases Axl/Tyro3.
Description

UNC2250 is a potent and selective Mer inhibitor with IC50 of 1.7 nM, about 160- and 60-fold selectivity over the closely related kinases Axl/Tyro3.
Synonyms

UNC2250, UNC-2250, UNC 2250
Pathway

Tyrosine Kinase
Target

TAM Receptor
Recptor

AXL; Mer; Tyro3
Research Area

Cancer
Indication

——

CAS Number

1493694-70-4
Formula Weight

440.58
Molecular Formula

C24H36N6O2
Purity

>98%(HPLC)
Solubility

DMSO: 2 mg/mL warmed (4.53 mM)
SMILES

O[C@H]1CC[C@H](NC2=NC(NCCCC)=NC=C2C3=NC=C(CN4CCOCC4)C=C3)CC1
Chemical Name

(1r,4r)-4-((2-(butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol

1.Zhang W, et al. J Med Chem. 2013, 56(23), 9683-9692.

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