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RU-302

CAS No. 1182129-77-6

RU-302 ( [2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]phenyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone )

Catalog No. M26815 CAS No. 1182129-77-6

RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 79 Get Quote
5MG 132 Get Quote
10MG 230 Get Quote
25MG 410 Get Quote
50MG 605 Get Quote
100MG 860 Get Quote
500MG 1728 Get Quote
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Biological Information

  • Product Name
    RU-302
  • Note
    Research use only, not for human use.
  • Brief Description
    RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain.
  • Description
    RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks the activation of Gas6-inducible AXL and suppresses lung cancer tumor growth.
  • Synonyms
    [2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]phenyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
  • Pathway
    Tyrosine Kinase
  • Target
    TAM Receptor
  • Recptor
    neuropeptide S receptor (NPSR)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1182129-77-6
  • Formula Weight
    475.5
  • Molecular Formula
    C24H24F3N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1noc(C)c1CSc1ccccc1C(=O)N1CCN(CC1)c1cccc(c1)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Batran RZ, et al. New quinolone derivatives as neuropeptide S receptor antagonists: Design, synthesis, homology modeling, dynamic simulations and modulation of Gq/Gs signaling pathways. Bioorg Chem. 2021;111:104817.
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