UNC1215

CAS No. 1415800-43-9

UNC1215 ( UNC 1215;UNC-1215 )

Catalog No. M11729 CAS No. 1415800-43-9

A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 42 In Stock
5MG 61 In Stock
10MG 105 In Stock
25MG 246 In Stock
50MG 380 In Stock
100MG 563 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    UNC1215
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM.
  • Description
    A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM; 50-fold more potent toward L3MBTL3 than other members of the MBT family; directly binds to L3MBTL3 via the Kme-binding pocket of the MBT domains.
  • Synonyms
    UNC 1215;UNC-1215
  • Pathway
    Chromatin/Epigenetic
  • Target
    HMTase
  • Recptor
    L3MBTL3;L3MBTL3-D274A
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    1415800-43-9
  • Formula Weight
    529.72
  • Molecular Formula
    C32H43N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 270 mg/mL
  • SMILES
    O=C(C1=CC=C(C(N2CCC(N3CCCC3)CC2)=O)C=C1NC4=CC=CC=C4)N5CCC(N6CCCC6)CC5
  • Chemical Name
    Methanone, 1,1'-[2-(phenylamino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. James LI, et al. Nat Chem Biol. 2013 Mar;9(3):184-91.
molnova catalog
related products
  • T1551

    T1551 is a novel, potent and specific PRMT5 inhibitor with IC50 of 34.1 uM.

  • EPZ6438

    EPZ-6438 is a potent, and selective EZH2 inhibitor with Ki and IC50 of 2.5 nM and 11 nM in cell-free assays.

  • JQEZ-5

    A novel potent, selective, SAM-competitive EZH2 inhibitor with IC50 of 80 nM (inhibition of enzymatic function of PRC2).