Cart
sales@molnova.com
Home - Products - Cytoskeleton/Cell Adhesion Molecules - Kinesin - UMK57

UMK57

CAS No. 342595-74-8

UMK57( —— )

Catalog No. M34457 CAS No. 342595-74-8

UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds, and can improve chromosome separation conservation by disrupting the stability of kinetosomal microtubule (k-MT) attachment during mitosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 87 In Stock
10MG 136 In Stock
25MG 233 In Stock
50MG 345 In Stock
100MG 502 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    UMK57
  • Note
    Research use only, not for human use.
  • Brief Description
    UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds, and can improve chromosome separation conservation by disrupting the stability of kinetosomal microtubule (k-MT) attachment during mitosis.
  • Description
    UMK57 is a small molecule compound that specifically promotes k-MT attachment error correction to inhibit chromosome missegregation, which can improve chromosome segregation fidelity by destabilizing kinetochore microtubule (k-MT) attachment during mitosis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Kinesin
  • Recptor
    Kinesin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    342595-74-8
  • Formula Weight
    295.4
  • Molecular Formula
    C17H17N3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Ethanol : 6.67 mg/mL (22.58 mM; Ultrasonic)DMSO : 2 mg/mL (6.77 mM; Ultrasonic (<60°C)
  • SMILES
    CC1=CC=C(C=C1)C1=CSC2=C1C(=NC=N2)N1CCCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bernardo Orr, et al. Adaptive Resistance to an Inhibitor of Chromosomal Instability in Human Cancer Cells. Cell Rep. 2016 Nov 8;17(7):1755-1763.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Azaperone

    Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.

  • Paprotrain

    Paprotrain inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.

  • Kif15-IN-2

    Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.

Sign In Join Free