Cart
sales@molnova.com
UF-010
CAS No. 537672-41-6
UF-010 ( UF010;UF 010 )
Catalog No. M14914 CAS No. 537672-41-6
A potent and selective inhibitor of class I HDACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 41 | In Stock |
|
| 25MG | 77 | In Stock |
|
| 50MG | 133 | In Stock |
|
| 100MG | 222 | In Stock |
|
| 200MG | 289 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameUF-010
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent and selective inhibitor of class I HDACs.
-
DescriptionA potent and selective inhibitor of class I HDACs with IC50s of 0.5/0.1/0.06/1.5/9.1/15.3/44.5 uM for HDAC1/2/3/8/6/10/11 respectively; shows no effect on HDAC4/5/7/9(>100 uM); induces the accumulation of protein acetylation and inhibits proliferation of NCI-60 panel of cancer cell lines (mean GI50=2.94 uM); a competitive with a fast-on/slow-off HDAC-binding mechanism.
-
SynonymsUF010;UF 010
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
RecptorHDAC
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number537672-41-6
-
Formula Weight271.15
-
Molecular FormulaC11H15BrN2O
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESO=C(NNCCCC)C1=CC=C(Br)C=C1
-
Chemical NameBenzoic acid, 4-bromo-, 2-butylhydrazide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wang Y, et al. Chem Biol. 2015 Feb 19;22(2):273-84.
molnova catalog
related products
-
Rocilinostat
Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay.
-
HDAC6 inhibitor NCT-...
A potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.
-
SB-429201
A potent, selective HDAC1 inhibitor with IC50 of 1.5 uM.
