UF-010

CAS No. 537672-41-6

UF-010 ( UF010;UF 010 )

Catalog No. M14914 CAS No. 537672-41-6

A potent and selective inhibitor of class I HDACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 41 In Stock
25MG 77 In Stock
50MG 133 In Stock
100MG 222 In Stock
200MG 289 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    UF-010
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective inhibitor of class I HDACs.
  • Description
    A potent and selective inhibitor of class I HDACs with IC50s of 0.5/0.1/0.06/1.5/9.1/15.3/44.5 uM for HDAC1/2/3/8/6/10/11 respectively; shows no effect on HDAC4/5/7/9(>100 uM); induces the accumulation of protein acetylation and inhibits proliferation of NCI-60 panel of cancer cell lines (mean GI50=2.94 uM); a competitive with a fast-on/slow-off HDAC-binding mechanism.
  • Synonyms
    UF010;UF 010
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    537672-41-6
  • Formula Weight
    271.15
  • Molecular Formula
    C11H15BrN2O
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(NNCCCC)C1=CC=C(Br)C=C1
  • Chemical Name
    Benzoic acid, 4-bromo-, 2-butylhydrazide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang Y, et al. Chem Biol. 2015 Feb 19;22(2):273-84.
molnova catalog
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