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Tyrosinase-IN-12

CAS No. 1860779-42-5

Tyrosinase-IN-12( —— )

Catalog No. M37195 CAS No. 1860779-42-5

Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) is a potent non-competitive tyrosinase inhibitor with an IC50 of 49.33 ± 2.64 μM and a Ki of 31.25 ± 0.25 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tyrosinase-IN-12
  • Note
    Research use only, not for human use.
  • Brief Description
    Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) is a potent non-competitive tyrosinase inhibitor with an IC50 of 49.33 ± 2.64 μM and a Ki of 31.25 ± 0.25 μM.
  • Description
    Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC50 value of 49.33 ± 2.64 μM and Ki value of 31.25 ± 0.25 μM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species (ROS) with an IC50 value of 25.39 ± 0.77 μM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors.
  • In Vitro
    Cell Viability Assay Cell Line:fresh-cut potato slices Concentration:Incubation Time:3 day Result:Exhibited browning inhibition effects close to those of kojic acid on fresh-cut potato slices.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Tyrosinase
  • Recptor
    Tyrosinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1860779-42-5
  • Formula Weight
    313.8
  • Molecular Formula
    C16H12ClN3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (159.34 mM; Ultrasonic )
  • SMILES
    N(/N=C/C1=CC=C(Cl)C=C1)C2=NC(=CS2)C3=CC=CC=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Djafarou S, et al. Synthesis and evaluation of the antioxidant and anti-tyrosinase activities of thiazolyl hydrazone derivatives and their application in the anti-browning of fresh-cut potato. Food Chem.
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