Cart
sales@molnova.com
Tucidinostat
CAS No. 1616493-44-7
Tucidinostat ( Chidamide;HBI-8000;CS055 )
Catalog No. M12363 CAS No. 1616493-44-7
Tucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 52 | In Stock |
|
| 10MG | 83 | In Stock |
|
| 25MG | 154 | In Stock |
|
| 50MG | 249 | In Stock |
|
| 100MG | 399 | In Stock |
|
| 200MG | 559 | In Stock |
|
| 500MG | 833 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTucidinostat
-
NoteResearch use only, not for human use.
-
Brief DescriptionTucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor.
-
DescriptionTucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor with IC50 of 95/160/67/733/78/432 nM for HDAC1/2/3/8/10/11, respectively; shows no activity against Class IIa HDAC4/4/7/9 and HDAC6; demonstrates significant and broad spectrum in vitro and in vivo antitumor activity, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells.Blood Cancer Approved
-
SynonymsChidamide;HBI-8000;CS055
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
RecptorHDAC1;HDAC2;HDAC3;HDAC10
-
Research AreaCancer
-
IndicationBlood cancer
Chemical Information
-
CAS Number1616493-44-7
-
Formula Weight390.42
-
Molecular FormulaC22H19FN4O2
-
Purity>98% (HPLC)
-
SolubilityEthanol: 1 mg/mL Water: InsolubleDMSO: 50 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )
-
SMILESO=C(NC1=CC=C(F)C=C1N)C2=CC=C(CNC(/C=C/C3=CC=CN=C3)=O)C=C2
-
Chemical NameN-(2-amino-4-fluorophenyl)-4-[[[(E)-3-pyridin-3-ylprop-2-enoyl]amino]methyl]benzamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ning ZQ, et al. Cancer Chemother Pharmacol. 2012 Apr;69(4):901-9.
2. Gong K, et al. Biochem J. 2012 May 1;443(3):735-46.
3. Dong M, et al. Cancer Chemother Pharmacol. 2012 Jun;69(6):1413-22.
4. Gao S, et al. Anticancer Agents Med Chem. 2017;17(6):802-812.
2. Gong K, et al. Biochem J. 2012 May 1;443(3):735-46.
3. Dong M, et al. Cancer Chemother Pharmacol. 2012 Jun;69(6):1413-22.
4. Gao S, et al. Anticancer Agents Med Chem. 2017;17(6):802-812.
molnova catalog
related products
-
MC-1568
A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.
-
Remodelin hydrobromi...
A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules.
-
1-Naphthohydroxamic ...
1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM).
