T326

CAS No. 1451042-19-5

T326 ( T 326;HDAC3 inhibitor T326 )

Catalog No. M11945 CAS No. 1451042-19-5

A potent and selective HDAC3 inhibitor with IC50 of 0.26 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    T326
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective HDAC3 inhibitor with IC50 of 0.26 uM.
  • Description
    A potent and selective HDAC3 inhibitor with IC50 of 0.26 uM, with no activity against HDAC1/4/6/8; induces dose-dependent selective increase of NF-κB acetylation in human colon cancer HCT116 cells, induces growth inhibition of cancer cells, and activates HIV gene expression in latent HIV-infected cells; shows promising activity for anticancer and antiviral benefits.
  • Synonyms
    T 326;HDAC3 inhibitor T326
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1451042-19-5
  • Formula Weight
    434.47
  • Molecular Formula
    C21H18N6O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C1=CC=C(C2=CN(CCC3=CC=CC([N+]([O-])=O)=C3)N=N2)S1)NC4=CC=CC=C4N
  • Chemical Name
    N-(2-aminophenyl)-5-(1-(3-nitrophenethyl)-1H-1,2,3-triazol-4-yl)thiophene-2-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Suzuki T, et al. PLoS One. 2013 Jul 16;8(7):e68669.
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